The track, arguably her biggest hit, has now stopped drawing an emotional reaction from O'Connor.

Writing on Facebook, the singer said:

"OK, the time has come for me to cease singing Nothing Compares 2U. The first principle of the manner in which I'm trained as a singer (Bel Canto) is we never sing a song we don't emotionally identify with. After twenty-five years of singing it, nine months or so ago I finally ran out of anything I could use in order to bring some emotion to it. I don't want audiences to be disappointed coming along to a show and then not hearing it, so am letting you know here that you won't. If I were to sing it just to please people, I wouldn't be doing my job right, because my job is to be emotionally available. I'd be lying. You'd be getting a lie. My job is to give you honesty. I'm trained in honesty. I can't act. It just isn't in my training. I have ceased singing other songs over the years for the same reason."

Watch the video for "Nothing Compares 2 U" below.